目的

探讨血清降钙素原（PCT） 在细菌性肝脓肿经皮引流治疗中的临床价值。

方法

回顾性分析经皮穿刺引流术确诊的38例细菌性肝脓肿患者的临床资料， 对术前血清PCT、 白细胞（WBC） 、 中性粒细胞百分比（NE%） 及血培养、 引流脓液培养结果进行分析。

结果

将38例细菌性肝脓肿患者根据血培养结果分为阳性组（8 例） 与阴性组（30 例） ， 两组年龄、 性别、 WBC和NE% 差异均无统计学意义（P均﹥0.05） ； 而阳性组PCT高于阴性组（P ﹤0.05） 。

结论

细菌性肝脓肿血培养阳性患者的血清PCT明显增高， 可以作为肝脓肿患者需加强抗生素治疗， 并尽快进行经皮穿刺引流的重要指征之一， 较血常规检查中WBC和NE% 有明显优势。

Objective

To explore clinical value of serum procalcitonin（PCT）in patients with bacterial liver abscess treated by percutaneous drainage.

Methods

Data of 38 patients with bacterial liver abscess treated by percutaneous drainage was retrospectively analyzed.The results of serum PCT，white blood cell（WBC）percentage of neutrophile granulocyte（NE%），blood cultures and bacterial culture of pyogenic fluids were analyzed.

Results

The 38 patients were divided into the positive group（n=8）and the negative group（n=30）according to the results of blood cultures.There was no significant difference in age，gender，WBC and NE%between the two groups（all P﹥0.05）.PCT in positive group was higher than that in negative group（P﹤0.05）.

Conclusions

The PCT value increased significantly in patients with bacterial liver abscess and positive blood cultures. PCT is superior to WBC and NE%，and it can be used as an important indication to enhance antibiotic treatment and prompt percutaneous drainage.